Dysregulation of follicle development in a mouse model of premature ovarian insufficiency
نویسندگان
چکیده
منابع مشابه
Dysregulation of follicle development in a mouse model of premature ovarian insufficiency
Premature ovarian insufficiency (POI) occurs in 1% of reproductive-age women. The ovarian manifestation ranges from the presence of a variable population of follicles (follicular) to the absence of follicles (afollicular), and in the majority of cases the cause is unknown. A transgenic mouse model of follicular POI, the Double Mutant (DM), arises from oocyte-specific deletion of Mgat1 and C1gal...
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15 صفحه اولA mouse model of premature ovarian insufficiency induced by tripterygium glycoside via subcutaneous injection.
Premature ovarian insufficiency (POI) is a main cause of infertility and affects nearly 1% women under 40 years old. This study was aimed to utilize the side effects of tripterygium glycoside (TG) to induce a mouse model of POI. 48 female KM mice were divided into four groups: control, oral, intraperitoneal injection and subcutaneous injection group. The mice in last three groups were treated w...
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ژورنال
عنوان ژورنال: Reproduction
سال: 2016
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-16-0091